Linker Information
General Information of This Linker
| Linker ID |
LIN0AGJKS
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| Linker Name |
T-4 linker
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C30H39N5O17S
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| Isosmiles |
O[C@@H]1[C@H](O)[C@@H](O)C(OC2=C(OS(=O)(O)=O)C=C(C(NCCOCCCN3C=C(N=N3)COCCOCCCN4C(C=CC4=O)=O)=O)C=C2)O[C@@H]1C(O)=O
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| InChI |
InChI=1S/C30H39N5O17S/c36-22-5-6-23(37)35(22)9-2-11-48-13-14-49-17-19-16-34(33-32-19)8-1-10-47-12-7-31-28(41)18-3-4-20(21(15-18)52-53(44,45)46)50-30-26(40)24(38)25(39)27(51-30)29(42)43/h3-6,15-16,24-27,30,38-40H,1-2,7-14,17H2,(H,31,41)(H,42,43)(H,44,45,46)/t24-,25+,26+,27-,30?/m0/s1
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| InChIKey |
CYAGFKTZMFSEST-WBJXAXNXSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
773.727
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Polar area
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304.93
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Complexity
|
1626.648592
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xlogp Value
|
-2.5843
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Heavy Count
|
53
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Rot Bonds
|
22
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Hbond acc
|
18
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker