Linker Information
General Information of This Linker
| Linker ID |
LIN0ABARV
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|---|---|---|---|---|---|---|
| Linker Name |
EP4183421A1+Trastuzumab-DXD+Linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C26H34N6O8
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| Isosmiles |
O=C(NCC(N[C@H](C(NCC(NCO)=O)=O)CC1=CC=CC=C1)=O)CNC(CCCCCN2C(C=CC2=O)=O)=O
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| PubChem CID | ||||||
| InChI |
InChI=1S/C26H34N6O8/c33-17-30-22(36)15-29-26(40)19(13-18-7-3-1-4-8-18)31-23(37)16-28-21(35)14-27-20(34)9-5-2-6-12-32-24(38)10-11-25(32)39/h1,3-4,7-8,10-11,19,33H,2,5-6,9,12-17H2,(H,27,34)(H,28,35)(H,29,40)(H,30,36)(H,31,37)/t19-/m0/s1
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| InChIKey |
ZYOKCRILRKJCIE-IBGZPJMESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
558.592
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Polar area
|
203.11
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Complexity
|
1038.515346
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xlogp Value
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-2.3861
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Heavy Count
|
40
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Rot Bonds
|
17
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker