Linker Information
General Information of This Linker
| Linker ID |
LIN0AAHUM
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|---|---|---|---|---|---|---|
| Linker Name |
L102 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C27H38N6O8
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| Isosmiles |
CC(C)[C@H](NC(CCOCCN1C(C=CC1=O)=O)=O)C(N[C@H](C(NC2=CC=C(CO)C=C2)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C27H38N6O8/c1-17(2)24(32-21(35)11-14-41-15-13-33-22(36)9-10-23(33)37)26(39)31-20(4-3-12-29-27(28)40)25(38)30-19-7-5-18(16-34)6-8-19/h5-10,17,20,24,34H,3-4,11-16H2,1-2H3,(H,30,38)(H,31,39)(H,32,35)(H3,28,29,40)/t20-,24-/m0/s1
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| InChIKey |
AKUCZXRMOZJSAR-RDPSFJRHSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
574.635
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Polar area
|
209.26
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Complexity
|
1051.539999
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xlogp Value
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-0.4768
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Heavy Count
|
41
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Rot Bonds
|
17
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker