Antibody Information
General Information of This Antibody
| Antibody ID | ANTI0EBUTO |
|||||
|---|---|---|---|---|---|---|
| Antibody Name | Anti-mouse PD-L1 (B7-H1) |
|||||
| Synonyms |
Anti-mouse PD-L1 (B7-H1)
Click to Show/Hide
|
|||||
| Antigen Name | Programmed cell death 1 ligand 1 (CD274) |
Antigen Info | ||||
| Click to Show/Hide the Sequence Information of This Antibody | ||||||
Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
wO2023232144A1ADC38 [Investigative]
Discovered Using Cell Line-derived Xenograft Model
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Max Tumor Growth lnhibition value (TGl) (d) |
20-50 %
|
Positive TLR expression (TLR+++/++) | ||
| Method Description |
ADC38 was tested in mouse M38 CRC model in C57BL/6 mice, 2.5 mg/kg, QWx3, IV
|
||||
| In Vivo Model | Mouse MC38 CRC Model in C57BL/6 Mice | ||||
wO2023232144A1ADC39 [Investigative]
Discovered Using Cell Line-derived Xenograft Model
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Max Tumor Growth lnhibition value (TGl) (d) |
20-50 %
|
Positive TLR expression (TLR+++/++) | ||
| Method Description |
ADC39 was tested in mouse M38 CRC model in C57BL/6 mice, 2.5 mg/kg, QWx3, IV
|
||||
| In Vivo Model | Mouse MC38 CRC Model in C57BL/6 Mice | ||||
wO2023232144A1ADC40 [Investigative]
Discovered Using Cell Line-derived Xenograft Model
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Max Tumor Growth lnhibition value (TGl) (d) | > 50% | Positive TLR expression (TLR+++/++) | ||
| Method Description |
ADC40 was tested in mouse M38 CRC model in C57BL/6 mice, 2.5 mg/kg, QWx3, IV
|
||||
| In Vivo Model | Mouse MC38 CRC Model in C57BL/6 Mice | ||||
wO2023232144A1ADC41 [Investigative]
Discovered Using Cell Line-derived Xenograft Model
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Max Tumor Growth lnhibition value (TGl) (d) | > 50% | Positive TLR expression (TLR+++/++) | ||
| Method Description |
ADC41 was tested in mouse M38 CRC model in C57BL/6 mice, 2.5 mg/kg, QWx3, IV
|
||||
| In Vivo Model | Mouse MC38 CRC Model in C57BL/6 Mice | ||||
References