Antibody Information
General Information of This Antibody
| Antibody ID | ANTI0DLSVM |
|||||
|---|---|---|---|---|---|---|
| Antibody Name | Sibrotuzumab |
|||||
| Synonyms |
Sibrotuzumab
Click to Show/Hide
|
|||||
| Antigen Name | Prolyl endopeptidase FAP (FAP) |
Antigen Info | ||||
| Click to Show/Hide the Sequence Information of This Antibody | ||||||
Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
nAPC-ADC [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
575.8 nM
|
High FAP expression (+++) | ||
| Method Description |
the half-maximal inhibitory concentration (IC50) of NAPC-ADC against 4T1-FAP cells
|
||||
| In Vitro Model | Malignant neoplasms of the mouse mammary gland | 4T1-FAP cells | CVCL_0125 | ||