Antibody Information

General Information of This Antibody

Antibody ID	ANI0LULKR
Antibody Name	12A11-TG6
Antibody Type	Monoclonal antibody (mAb)
Antibody Subtype	Humanized IgG1-kappa
Antigen Name	C-X-C chemokine receptor type 4 (CXCR4)	Antigen Info

Each Antibody-drug Conjugate Related to This Antibody

Full Information of The Activity Data of The ADC(s) Related to This Antibody

12A11-TG6-vcMMAD [Investigative]

ADC Info

Revealed Based on the Cell Line Data

Click To Hide/Show 1 Activity Data Related to This Level

Experiment 1 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Inhibitory Concentration (IC50)	1.87 nM	Positive CXCR4 expression (CXCR4+++/++)
Method Description	Cells were incubated with increasing concentrations of each ADCs at 37°C for 6 days in complete culture medium.
In Vitro Model	Burkitt lymphoma	Ramos cells		CVCL_0597

References

Ref 1	Anti-cxcr4 antibodies and antibody-drug conjugates.

If you find any error in data or bug in web service, please kindly report it to Dr. Shen et al.