Antibody Information

General Information of This Antibody

Antibody ID	ANI0BYCUP
Antibody Name	Murine mAb B3
Antibody Type	Monoclonal antibody (mAb)
Antibody Subtype	Murine IgG
Antigen Name	Poly [ADP-ribose] polymerase 1 (PARP1)	Antigen Info

Each Antibody-drug Conjugate Related to This Antibody

Full Information of The Activity Data of The ADC(s) Related to This Antibody

LMB-7 [Terminated in phase 1]

ADC Info

Identified from the Human Clinical Data

Click To Hide/Show 1 Activity Data Related to This Level

Experiment 1 Reporting the Activity Date of This ADC				[1]
Patients Enrolled	Patients with leptomeningeal metastases.
*Related Clinical Trial*
NCT Number	NCT00003020	Clinical Status	Phase 1
Clinical Description	Phase 1 dose-escalation study of intravenous CMD-193 in subjects with advanced malignant solid tumors.

References

Ref 1	Protocol for a Phase I Study of Intrathecal LMB-7 (Single-Chain Immunotoxin Constructed From Monoclonal Antibody B3-Pseudomonas Exotoxin PE 38) [IND 5863, NSC 658931] in the Treatment of Patients With Leptomeningeal Neoplasms

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