Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0VSCGT
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| ADC Name |
EP4090377A1 B12-v1a-145-PF01
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| Synonyms |
B12-v1a-145-PF01
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| Organization |
SYNAFFIX B.V.
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| Drug Status |
Investigative
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| Antibody Name |
BCN-B12 B12-v1a-145
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Antibody Info | ||||
| Antigen Name |
T-cell surface glycoprotein CD3 (CD3)
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Antigen Info | ||||
| Payload Name |
Undisclosed
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Payload Info | ||||
| Linker Name |
Undisclosed
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| Conjugate Type |
DBCO-Azide Click Chemistry Conjugation
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| Combination Type |
HOKT3-PEG11-tetrazine PF01
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General Information of The Activity Data Related to This ADC
Full List of Activity Data of This Antibody-drug Conjugate
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
741 pM
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| Method Description |
The bispecific effect of hOKT3200 on human PBMC killing RajiB tumor cells. The bispecific and calculated EC50 values are shown in the legend.
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| In Vitro Model | Normal | PBMC cells | CVCL_0140 | ||