Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0RCHUM
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| ADC Name |
RG-7600
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| Synonyms |
DMOT-4039A; RG7600; RG 7600; DMOT 4039A
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| Organization |
Genentech, Inc.; Roche Holding AG
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| Drug Status |
Terminated in phase 1
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| Indication |
In total 2 Indication(s)
Ovarian cancer [ICD11:2C73]
Terminated in phase 1
Pancreatic cancer [ICD11:2C10]
Terminated in phase 1
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| Drug-to-Antibody Ratio |
3.5
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| Antibody Name |
Humanized IgG1 Anti-MSLN mAb h7D9.v3
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Antibody Info | ||||
| Antigen Name |
Mesothelin (MSLN)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Therapeutic Target |
Microtubule (MT)
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Target Info | ||||
| Linker Name |
Protease-labile valine-citrulline linker
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Linker Info | ||||
| Puchem SID | ||||||
| ChEBI ID | ||||||
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