Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0ESREW
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| ADC Name |
IGF-MTX
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| Synonyms |
IGFMTX; IGF MTX; IGF-drug conjugates(IGF Oncology LLC); IGF-drug conjugates
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| Organization |
IGF Oncology LLC
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| Drug Status |
Phase 1/2
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| Indication |
In total 1 Indication(s)
Phase 1/2
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| Antibody Name |
Anti-IGF1R mAb
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Antibody Info | ||||
| Antigen Name |
Insulin-like growth factor 1 receptor (IGF1R)
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Antigen Info | ||||
| Payload Name |
Methotrexate
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Payload Info | ||||
| Therapeutic Target |
Dihydrofolate reductase (DHFR)
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Target Info | ||||
| Linker Name |
Undisclosed
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| TTD ID | ||||||
General Information of The Activity Data Related to This ADC
Full List of Activity Data of This Antibody-drug Conjugate
Discovered Using Cell Line-derived Xenograft Model
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Tumor Growth Inhibition value (TGI) | ≈ 98.34% | |||
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