Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
ADC ID |
DRG0ESREW
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ADC Name |
IGF-MTX
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Synonyms |
IGFMTX; IGF MTX; IGF-drug conjugates(IGF Oncology LLC); IGF-drug conjugates
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Organization |
IGF Oncology LLC
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Drug Status |
Phase 1/2
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Indication |
In total 1 Indication(s)
Myelodysplastic syndrome [ICD11:2A37]
Phase 1/2
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Antibody Name |
Anti-IGF1R mAb
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Antibody Info | ||||
Antigen Name |
Insulin-like growth factor 1 receptor (IGF1R)
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Antigen Info | ||||
Payload Name |
Methotrexate
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Payload Info | ||||
Therapeutic Target |
Dihydrofolate reductase (DHFR)
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Target Info | ||||
Linker Name |
Undisclosed
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TTD ID |
General Information of The Activity Data Related to This ADC
Full List of Activity Data of This Antibody-drug Conjugate
Discovered Using Cell Line-derived Xenograft Model
Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
Efficacy Data | Tumor Growth Inhibition value (TGI) | ≈ 98.34% |
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