Antigen Information
General Information of This Antigen (ID: TAR0XTVJE)
| Antigen Name | Tax1-binding protein 3 (TAX1BP3) |
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| Gene Name | TAX1BP3 |
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| Gene ID | ||||||
| Synonym | Glutaminase-interacting protein 3;Tax interaction protein 1;Tax-interacting protein 1 |
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| Sequence |
MSYIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRV
SEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQ SMLS Click to Show/Hide
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| Function |
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
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Anti-TIP1 mAb 7H5
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
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7H5-Val-Cit-MMAE
[1]
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Monomethyl auristatin E |
Microtubule (MT) |
Mc-Val-Cit-PABC |
References