Antigen Information
General Information of This Antigen (ID: TAR0UNGLZ)
| Antigen Name | MHC class I polypeptide-related sequence A (MICA) |
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| Gene Name | MICA |
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| Gene ID | ||||||
| Sequence |
MGLGPVFLLLAGIFPFAPPGAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCD
RQKCRAKPQGQWAEDVLGNKTWDRETRDLTGNGKDLRMTLAHIKDQKEGLHSLQEIRVCE IHEDNSTRSSQHFYYDGELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHY HAMHADCLQELRRYLKSGVVLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWR QDGVSLSHDTQQWGDVLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHSTHPVPSGKV LVLQSHWQTFHVSAVAAAAIFVIIIFYVRCCKKKTSAAEGPELVSLQVLDQHPVGTSDHR DATQLGFQPLMSDLGSTGSTEGA Click to Show/Hide
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| Family | MHC class I family |
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| Function |
Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
Glycosylated Anti-MICA Anti-ody
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
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IPH43
[1]
|
PBD dimer |
Human Deoxyribonucleic acid (hDNA) |
Undisclosed |