General Information of This Antigen
Antigen ID
TAR0UBWTY
Antigen Name
Translocator protein (TSPO)
Gene Name
TSPO
Synonym
BZRP; MBR; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor
Sequence
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM
GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA
ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE

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Family
TspO/BZRP family
Function
Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral- type benzodiazepine receptor; can also bind isoquinoline carboxamides.

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Uniprot Entry
TSPO_HUMAN
HGNC ID
HGNC:1158
KEGG ID
hsa:706
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Anti-SAIL mAb
ADC Info ADC Name Payload Target Linker Ref
IGN-786
Monomethyl auristatin F
Microtubule (MT)
Maleimido-caproyl
[1]
References
Ref 1 Introduction to basic information on ADC drug IGN-786