Antigen Information
General Information of This Antigen
| Antigen ID | TAR0TEMBG |
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|---|---|---|---|---|---|---|
| Antigen Name | DNA-binding protein inhibitor ID-1 (ID1) |
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| Gene Name | ID1 |
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| Gene ID | ||||||
| Synonym | BHLHB24; ID |
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| Sequence |
MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQ
QVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGTPGG RGLPVRAPLSTLNGEISALTAEAACVPADDRILCR Click to Show/Hide
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| Function |
FUNCTION: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer (By similarity). {ECO:0000250}.
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| Uniprot Entry | ||||||
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Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
FeID1
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
FeID1- (AL7-LP1)n |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
US20240269308A1 aHer2- (AL6-LP1)n Linker |
[1] | |
FeID1- (AL7-LP13)n |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
US20240269308A1 aHer2- (AL6-LP13)n Linker |
[1] | |
FeID1- (AL7-LP2)n |
CP1412 |
Undisclosed |
US20240269308A1 aHer2- (AL6-LP1)n Linker |
[1] | |
FeID1- (AL7-LP3)n |
CP1408 |
Undisclosed |
US20240269308A1 aHer2- (AL6-LP1)n Linker |
[1] | |
FeID1- (AL7-LP4)n |
CP1409 |
Undisclosed |
US20240269308A1 aHer2- (AL6-LP1)n Linker |
[1] | |
FeID1- (AL7-LP5)n |
CP1436 |
DNA topoisomerase I (TOP1) |
US20240269308A1 aHer2- (AL7-LP5)n Linker |
[1] | |
FeID1- (AL7-LP7)n |
CP1411 |
Undisclosed |
US20240269308A1 aHer2- (AL7-LP5)n Linker |
[1] | |
FeID1- (AL7-LP9)n |
CP1422 |
Undisclosed |
US20240269308A1 aHer2- (AL7-LP5)n Linker |
[1] | |
FeID1- (AL7-LP12)n |
CP1436 |
DNA topoisomerase I (TOP1) |
US20240269308A1 aHer2- (AL7-LP5)n Linker |
[1] | |
FeID1- (AL7-LP5D)n |
CP1436 |
DNA topoisomerase I (TOP1) |
US20240269308A1 aHer2- (AL7-LP5D)n Linker |
[1] | |
FeID1- (AL4c-LP1B)n |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
US20240269308A1 aHer2- (AL4c-LP1B)n Linker |
[1] | |
FeID1- (AL4c-LP13C)n |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
US20240269308A1 aHer2- (AL4c-LP13C)n Linker |
[1] | |
FeID1- (AL11a-LP1)n |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
US20240269308A1 aHer2- (AL6-LP1)n Linker |
[1] | |
FeID1- (AL11a-LP13)n |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
US20240269308A1 aHer2- (AL6-LP13)n Linker |
[1] | |
FeID1- (AL11a-LP15)n |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
US20240269308A1 aHer2- (AL6-LP15)n Linker |
[1] | |
FeID1- (BL1-LP1)n |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
US20240269308A1 aHer2- (AL6-LP1)n Linker |
[1] | |
FeID1- (BL1-LP13)n |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
US20240269308A1 aHer2- (AL6-LP13)n Linker |
[1] | |
FeID1- (BL3b-LP1)n |
DX-8951 derivative (DXd) |
DNA topoisomerase 1 (TOP1) |
US20240269308A1 aHer2- (AL6-LP1)n Linker |
[1] |
References