General Information of This Antigen
Antigen ID
TAR0SBVOW
Antigen Name
C-C motif chemokine 1 (CCL1)
Gene Name
CCL1
Gene ID
6346
Synonym
SCYA1; Small-inducible cytokine A1; T lymphocyte-secreted protein I-309
Sequence
MQIITTALVCLLLAGMWPEDVDSKSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSICSNE
GLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK

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Family
Intercrine beta (chemokine CC) family
Function
Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.

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Uniprot Entry
CCL1_HUMAN
HGNC ID
HGNC:10609
KEGG ID
hsa:6346
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Anti-CLL1 mAb
ADC Info ADC Name Payload Target Linker Ref
CLL1-5 ADC
GNE-987 (R)
Bromodomain-containing protein 4 (BRD4)
Dolaflexin polymer
[1]
CLL1-6 ADC
GNE-987 (S)
Bromodomain-containing protein 4 (BRD4)
Dolaflexin polymer
[1]
References
Ref 1 Antibody Conjugation of a Chimeric BET Degrader Enables in?vivo Activity. ChemMedChem. 2020 Jan 7;15(1):17-25. doi: 10.1002/cmdc.201900497. Epub 2019 Nov 14.