General Information of This Antigen (ID: TAR0SBVOW)
Antigen Name
C-C motif chemokine 1 (CCL1)
Gene Name
CCL1
Gene ID
6346
Synonym
SCYA1; Small-inducible cytokine A1; T lymphocyte-secreted protein I-309
Sequence
MQIITTALVCLLLAGMWPEDVDSKSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSICSNE
GLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK

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Family
Intercrine beta (chemokine CC) family
Function
Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.

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Uniprot Entry
CCL1_HUMAN
HGNC ID
HGNC:10609
KEGG ID
hsa:6346
Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens
Anti-CLL1 mAb
ADC Name Payload Target Linker ADC Info
CLL1-5 ADC [1]
GNE-987 (R)
Bromodomain-containing protein 4 (BRD4)
Dolaflexin polymer
CLL1-6 ADC [1]
GNE-987 (S)
Bromodomain-containing protein 4 (BRD4)
Dolaflexin polymer
References
Ref 1 Antibody Conjugation of a Chimeric BET Degrader Enables in?vivo Activity. ChemMedChem. 2020 Jan 7;15(1):17-25. doi: 10.1002/cmdc.201900497. Epub 2019 Nov 14.