Antigen Information
General Information of This Antigen
| Antigen ID | TAR0RYGBQ |
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| Antigen Name | Claudin-6 (CLDN6); Claudin-9 (CLDN9) |
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| Gene Name | CLDN6; CLDN9 |
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| Gene ID | ||||||
| Synonym1 | Claudin-6, Skullin |
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| Synonym2 | Claudin-9 |
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| Sequence1 |
MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG
QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV Click to Show/Hide
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| Sequence2 |
MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG
QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL LCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV Click to Show/Hide
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| Family1 | Claudin family |
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| Family2 | Claudin family |
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| Function1 |
Plays a major role in tight junction-specific obliteration of the intercellular space.
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| Function2 |
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells.
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| Uniprot Entry | ||||||
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Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
An antibody targeting CLDN6/9
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
SC-004 |
SGD-1882 |
Human deoxyribonucleic acid (hDNA) |
Val-Cit linker |
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SHR-7782 |
Undisclosed |
Undisclosed |
Undisclosed |
undisclosed
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
BLB-101 |
Undisclosed |
Undisclosed |
Undisclosed |
[1] |
References