Antigen Information
General Information of This Antigen (ID: TAR0MVKGL)
| Antigen Name | GDNF family receptor alpha-1 (GFRA1) |
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| Gene Name | GFRA1 |
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| Gene ID | ||||||
| Synonym | GDNFRA; RETL1; TRNR1; RET ligand 1;TGF-beta-related neurotrophic factor receptor 1 |
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| Sequence |
MFLATLYFALPLLDLLLSAEVSGGDRLDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNF
SLASGLEAKDECRSAMEALKQKSLYNCRCKRGMKKEKNCLRIYWSMYQSLQGNDLLEDSP YEPVNSRLSDIFRVVPFISDVFQQVEHIPKGNNCLDAAKACNLDDICKKYRSAYITPCTT SVSNDVCNRRKCHKALRQFFDKVPAKHSYGMLFCSCRDIACTERRRQTIVPVCSYEEREK PNCLNLQDSCKTNYICRSRLADFFTNCQPESRSVSSCLKENYADCLLAYSGLIGTVMTPN YIDSSSLSVAPWCDCSNSGNDLEECLKFLNFFKDNTCLKNAIQAFGNGSDVTVWQPAFPV QTTTATTTTALRVKNKPLGPAGSENEIPTHVLPPCANLQAQKLKSNVSGNTHLCISNGNY EKEGLGASSHITTKSMAAPPSCGLSPLLVLVVTALSTLLSLTETS Click to Show/Hide
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| Family | Folate receptor family |
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| Function |
Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
Anti-GFRA1 mAb
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
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GFRA1 targeted antibody-drug conjugate
[1]
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SG3199 |
Human Deoxyribonucleic acid (hDNA) |
Mal-PEG8-Val-Ala-PABC |
References