Antigen Information
General Information of This Antigen
| Antigen ID | TAR0MCXEX |
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| Antigen Name | Transmembrane glycoprotein NMB (GPNMB) |
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| Gene Name | GPNMB |
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| Synonym | HGFIN; NMB; Hematopoietic growth factor inducible neurokinin-1 type |
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| Sequence |
MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYP
VWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNC RNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTL GQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGRAYVPIAQVKDVYVVTDQIPVFV TMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVN HTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLE LSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSI PTEVCTIISDPTCEITQNTVCSPVDVDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTS TLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKG LSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS Click to Show/Hide
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| Family | PIEZO (TC 1.A.75) family |
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| Function |
Could be a melanogenic enzyme.
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| Uniprot Entry | ||||||
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Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Glembatumumab
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
Glembatumumab vedotin |
MMAE |
Microtubule (MT) |
Mc-Val-Cit-PABC |
HCR011
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
pF-08046033 |
Auristatin S |
Microtubule (MT) |
Mc-Val-Cit-PABC |
Undisclosed
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
A1801 |
Undisclosed |
Undisclosed |
Undisclosed |
[1] |