Antigen Information
General Information of This Antigen (ID: TAR0MCXEX)
| Antigen Name | Transmembrane glycoprotein NMB (GPNMB) |
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| Gene Name | GPNMB |
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| Gene ID | ||||||
| Synonym | HGFIN; NMB; Hematopoietic growth factor inducible neurokinin-1 type |
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| Sequence |
MECLYYFLGFLLLAARLPLDAAKRFHDVLGNERPSAYMREHNQLNGWSSDENDWNEKLYP
VWKRGDMRWKNSWKGGRVQAVLTSDSPALVGSNITFAVNLIFPRCQKEDANGNIVYEKNC RNEAGLSADPYVYNWTAWSEDSDGENGTGQSHHNVFPDGKPFPHHPGWRRWNFIYVFHTL GQYFQKLGRCSVRVSVNTANVTLGPQLMEVTVYRRHGRAYVPIAQVKDVYVVTDQIPVFV TMFQKNDRNSSDETFLKDLPIMFDVLIHDPSHFLNYSTINYKWSFGDNTGLFVSTNHTVN HTYVLNGTFSLNLTVKAAAPGPCPPPPPPPRPSKPTPSLATTLKSYDSNTPGPAGDNPLE LSRIPDENCQINRYGHFQATITIVEGILEVNIIQMTDVLMPVPWPESSLIDFVVTCQGSI PTEVCTIISDPTCEITQNTVCSPVDVDEMCLLTVRRTFNGSGTYCVNLTLGDDTSLALTS TLISVPDRDPASPLRMANSALISVGCLAIFVTVISLLVYKKHKEYNPIENSPGNVVRSKG LSVFLNRAKAVFFPGNQEKDPLLKNQEFKGVS Click to Show/Hide
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| Family | PIEZO (TC 1.A.75) family |
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| Function |
Could be a melanogenic enzyme.
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| Uniprot Entry | ||||||
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
Glembatumumab
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
Glembatumumab vedotin
|
Monomethyl auristatin E |
Microtubule (MT) |
Mc-Val-Cit-PABC |
HCR011
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
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PF-08046033
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Auristatin S |
Microtubule (MT) |
Mc-Val-Cit-PABC |
Undisclosed
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
A1801
[1]
|
Undisclosed |
Undisclosed |
Undisclosed |