Antigen Information
General Information of This Antigen
| Antigen ID | TAR0KRVBQ |
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| Antigen Name | Tumor necrosis factor receptor superfamily member 5 (CD40) |
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| Gene Name | CD40 |
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| Gene ID | ||||||
| Synonym | TNFRSF5; B-cell surface antigen CD40;Bp50;CD40L receptor;CDw40;CD_antigen=CD40 |
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| Sequence |
MVRLPLQCVLWGCLLTAVHPEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECL
PCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCV LHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTN KTDVVCGPQDRLRALVVIPIIFGILFAILLVLVFIKKVAKKPTNKAPHPKQEPQEINFPD DLPGSNTAAPVQETLHGCQPVTQEDGKESRISVQERQ Click to Show/Hide
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| Function |
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
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Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Anti-human CD40 MoAb G28-5
| ADC Info | ADC Name | Payload | Target | Linker | Ref |
|---|---|---|---|---|---|
G28-5 sFv-PE40 |
Pseudomonas exotoxin PE40 |
Eukaryotic elongation factor 2 kinase (EEF2K) |
Undisclosed |
[1] |
References