Antigen Information
General Information of This Antigen (ID: TAR0KRVBQ)
| Antigen Name | Tumor necrosis factor receptor superfamily member 5 (CD40) |
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| Gene Name | CD40 |
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| Synonym | TNFRSF5; B-cell surface antigen CD40;Bp50;CD40L receptor;CDw40;CD40 |
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| Sequence |
MVRLPLQCVLWGCLLTAVHPEPPTACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECL
PCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCV LHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTN KTDVVCGPQDRLRALVVIPIIFGILFAILLVLVFIKKVAKKPTNKAPHPKQEPQEINFPD DLPGSNTAAPVQETLHGCQPVTQEDGKESRISVQERQ Click to Show/Hide
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| Function |
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
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Anti-human CD40 MoAb G28-5
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
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G28-5 sFv-PE40
[1]
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Pseudomonas exotoxin PE40 |
Eukaryotic elongation factor 2 kinase (EEF2K) |
Undisclosed |
References