Antigen Information

General Information of This Antigen
Antigen ID
TAR0HSEFL
Antigen Name
Transmembrane 4 L6 family member 1 (TM4SF1)
Gene Name
TM4SF1
Gene ID
4071
Synonym
M3S1; TAAL6; Membrane component chromosome 3 surface marker 1;Tumor-associated antigen L6
Sequence
MCYGKCARCIGHSLVGLALLCIAANILLYFPNGETKYASENHLSRFVWFFSGIVGGGLLM
LLPAFVFIGLEQDDCCGCCGHENCGKRCAMLSSVLAALIGIAGSGYCVIVAALGLAEGPL
CLDSLGQWNYTFASTEGQYLLDTSTWSECTEPKHIVEWNVSLFSILLALGGIEFILCLIQ
VINGVLGGICGFCCSHQQQYDC

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Family
Interleukin-1 receptor family
Uniprot Entry
T4S1_HUMAN
HGNC ID
HGNC:11853
KEGG ID
hsa:4071
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Anti-TM4SF1 antibody
 Antibody Info 
ADC Name Payload Target Linker ADC Info
AGX101
Maytansine derivative
Microtubule (MT)
A non-cleavable linker
 ADC Info 
undisclosed
 Antibody Info 
ADC Name Payload Target Linker ADC Info
US20240166759A1 Antibody1-L1 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody1-L2 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody1-L3 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody1-L4 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody1-L5 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody1-L6 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody1-L7 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody2-L1 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody2-L2 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody2-L3 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody2-L4 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody2-L5 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody2-L6 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
US20240166759A1 Antibody2-L7 [1]
Undisclosed
Undisclosed
Undisclosed
 ADC Info 
BA-PEG4-N-methyl-alanine-Medandine [1]
Medandine
Undisclosed
Undisclosed
 ADC Info 
BA-PEG4-AHX-N-methyl-alanine-Medandine [1]
Medandine
Undisclosed
Undisclosed
 ADC Info 
BA-glucuronidin-N-methyl-alanine-Medandine [1]
Medandine
Undisclosed
Undisclosed
 ADC Info 
BA-Glu- (O-T-butyl) -glucuronoside - N-methyl-alanine - N-methyl-alanine - Medendine [1]
Medandine
Undisclosed
Undisclosed
 ADC Info 
BA-PEG4-D-Glu-0T-Butyl-AHX-N-methyl-alanine-Medandine [1]
Medandine
Undisclosed
Undisclosed
 ADC Info 
BA-PEG4-D-GLU-AHX-N-methyl-alanine-Medandine [1]
Medandine
Undisclosed
Undisclosed
 ADC Info 
BA-PEG4-D-GLU-N-methyl-alanine-Medandine [1]
Medandine
Undisclosed
Undisclosed
 ADC Info 
Undisclosed
 Antibody Info 
ADC Name Payload Target Linker ADC Info
IgG2a-PEG8-MMAE [2]
Monomethyl auristatin E
Microtubule (MT)
WO2024102603A1+lgG2a-PEG8-MMAE+Linker
 ADC Info 
References
Ref 1 Combinations comprising anti-TM4SF1 antibodies and immunotherapeutic agents and methods of using the same
Ref 2 Bisecting-glycan bridged conjugation for producing glycoprotein conjugates