Antigen Information

General Information of This Antigen (ID: TAR0HPZTL)
Antigen Name
Structural glycoprotein gp41 (GP41)
Gene Name
GP41
Synonym
GP41
Sequence
MTDERGNFYYNTPPPLRYPSNPATAIFTSAQTYNAPGYVPPATVPTTVATRDNRMDYTSR
SNSTNSVAIAPYNKSKEPTLDAGESIWYNKCVDFVQKIIRYYRCNDMSELSPLMILFINT
IRDMCIDTNPISVNVVKRFESEETMIRHLIRLQKELGQSNAAESLSSDSNIFQPSFVLNS
LPAYAQKFYNGGADMLGKDALAEAAKQLSLAVQYMVAEAVTCNIPIPLPFNQQLANNYMT
LLLKHATLPPNIQSAVESRRFPHINMINDLINAVIDDLFAGGGDYYHYVLNEKNRARVMS
LKENVAFLAPLSASANIFNYMAELATRAGKQPSMFQNATFLTSAANAVNSPAAHLTKSAC
QESLTELAFQNETLRRFIFQQINYNKDANAIIAAAAPNATRPNTKGRTA

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Family
Baculoviridae gp41 family
Function
FUNCTION: Major tegument protein that participates in the egress of nucleocapsids from the host nucleus. May be involved in host nucleus-cytoplasm transportation of nucleocapsids to form budded virion (BVs). {ECO:0000269|PubMed:29643237, ECO:0000269|PubMed:9217053}.

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Uniprot Entry
GP41_NPVAC
KEGG ID
vg:1403913
Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens
ADC Name Payload Target Linker ADC Info
39283123 7B2-PNU [1]
Undisclosed
Undisclosed
Mal-PEG4-Val-Ala-PABC
 ADC Info 
39283123 7B2-dgA [1]
Deglycosylated ricin A chain (dgA)
Undisclosed
Undisclosed
 ADC Info 
39283123 7B2-Calicheamicin [1]
Calicheamicin
Undisclosed
Undisclosed
 ADC Info 
39283123 7B2-Amanitin [1]
Amanitin
RNA polymerase II
Undisclosed
 ADC Info 
References
Ref 1 Conjugation of anti-HIV gp41 monoclonal antibody to a drug capable of targeting resting lymphocytes produces an effective cytotoxic anti-HIV immunoconjugate