Antigen Information

General Information of This Antigen
Antigen ID
TAR0GSSJV
Antigen Name
Pregnancy-specific beta-1-glycoprotein 2 (PSG2)
Gene Name
PSG2
Gene ID
5670
Synonym
PSBG2; Pregnancy-specific beta-1 glycoprotein E
Sequence
MGPLSAPPCTEHIKWKGLLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQ
NLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY
TLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCDPETPDTSYQW
WMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGPD
LPRIHPSYTNYRSGDNLYLSCFANSNPPAQYSWTINGKFQQSGQNLFIPQITTKHSGLYV
CSVRNSATGEESSTSLTVKVSASTRIGLLPLLNPT

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Family
BTN/MOG family
Uniprot Entry
PSG2_HUMAN
HGNC ID
HGNC:9519
KEGG ID
hsa:5670
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Anti-CEA mAb MIC0101
 Antibody Info 
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
Fluorescent Antibody-Drug Conjugate
Paclitaxel
Microtubule (MT)
Undisclosed
 [1]
Anti-CEACAM5 mAb A5B7
 Antibody Info 
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
Monoclonal antibody A5B7-cisplatin conjugate
Cisplatin
Human Deoxyribonucleic acid (hDNA)
Undisclosed
 [2]
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
CytSCA208
Cytorhodin S
DNA topoisomerase 2-alpha (TOP2A)
Undisclosed
 [3]
Undisclosed
 Antibody Info 
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
CEA ADC
Undisclosed
Undisclosed
Undisclosed
 [4]
References
Ref 1 Development and Evaluation of a Fluorescent Antibody-Drug Conjugate for Molecular Imaging and Targeted Therapy of Pancreatic Cancer. PLoS One. 2016 Jun 23;11(6):e0157762. doi: 10.1371/journal.pone.0157762. eCollection 2016.
Ref 2 Pharmacokinetics and tissue distribution of cisplatin and conjugates of cisplatin with carboxymethyldextran and A5B7 monoclonal antibody in CD1 mice. J Pharm Sci. 1997 Dec;86(12):1478-83. doi: 10.1021/js960282u.
Ref 3 Selective killing of carcinoembryonic-antigen (CEA)-producing cells in vitro by the immunoconjugate cytorhodin-S and CEA-reactive cytorhodin-S antibody CA208. Cancer Immunol Immunother. 1989;30(4):239-46. doi: 10.1007/BF01665011.
Ref 4 Introduction to basic information on ADC drug CEA ADC