General Information of This Antigen (ID: TAR0ESQBL)
Antigen Name
CD99 antigen (CD99)
Gene Name
CD99
Gene ID
4267
Synonym
MIC2; MIC2X; MIC2Y; 12E7;E2 antigen;Protein MIC2;T-cell surface glycoprotein E2;CD99
Sequence
MARGAALALLLFGLLGVLVAAPDGGFDLSDALPDNENKKPTAIPKKPSAGDDFDLGDAVV
DGENDDPRPPNPPKPMPNPNPNHPSSSGSFSDADLADGVSGGEGKGGSDGGGSHRKEGEE
ADAPGVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKENAEQGEVDMESHRNANAEPAVQR
TLLEK

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Family
Beta-2-microglobulin family
Function
Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes.

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Uniprot Entry
CD99_HUMAN
HGNC ID
HGNC:7082
KEGG ID
hsa:4267
Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens
Undisclosed
ADC Name Payload Target Linker ADC Info
NV103 [1]
Irinotecan
DNA topoisomerase 1 (TOP1)
Undisclosed
NV101 [2]
Doxorubicin
DNA topoisomerase 2-alpha (TOP2A)
Undisclosed
References
Ref 1 ADC review NV103
Ref 2 ADC review NV101