Antigen Information

General Information of This Antigen
Antigen ID
TAR0DQHIR
Antigen Name
Anthrax toxin receptor 2 (ANTXR2)
Gene Name
ANTXR2
Gene ID
118429
Synonym
Capillary morphogenesis gene 2 protein
Sequence
MVAERSPARSPGSWLFPGLWLLVLSGPGGLLRAQEQPSCRRAFDLYFVLDKSGSVANNWI
EIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLKRVSPVGETYI
HEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAEKEAKISRSLGASVYCVGVLD
FEQAQLERIADSKEQVFPVKGGFQALKGIINSILAQSCTEILELQPSSVCVGEEFQIVLS
GRGFMLGSRNGSVLCTYTVNETYTTSVKPVSVQLNSMLCPAPILNKAGETLDVSVSFNGG
KSVISGSLIVTATECSNGIAAIIVILVLLLLLGIGLMWWFWPLCCKVVIKDPPPPPAPAP
KEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPE
ETEEPIRPRPPRPKPTHQPPQTKWYTPIKGRLDALWALLRRQYDRVSLMRPQEGDEVCIW
ECIEKELTA

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Family
ARTD/PARP family
Function
Necessary for cellular interactions with laminin and the extracellular matrix.

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Uniprot Entry
ANTR2_HUMAN
HGNC ID
HGNC:21732
KEGG ID
hsa:118429
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Anti-ANTXR2 mAb H8R23
 Antibody Info 
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
H8R23-DT3C
Diphtheria toxin containing streptococcal protein G (DT3C)
Eukaryotic elongation factor 2 (EEF2)
Undisclosed
 [1]
References
Ref 1 Anthrax toxin receptor 2 is a potential therapeutic target for non-small cell lung carcinoma with MET exon 14 skipping mutations. Exp Cell Res. 2022 Apr 15;413(2):113078.

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