General Information of This Antigen (ID: TAR0DCTSO)
Antigen Name
Cell surface protein 1 (CSP-1)
Function
The cell surface protein named CSP-1 against which AG02 bound on the cell surface of selected cancer cells was identified by immunoprecipitation followed by mass spectrometry. Identified CSP-1 was demonstrated as being associated with metastatic potential thus emphasizing its potential as an important target for development of an anti-cancer agent. Upon binding to CSP-1, AG02 antibody internalized the CSP-1 target.

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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens
Anti-CSP-1 mAb AG02
ADC Name Payload Target Linker ADC Info
AG 02 saporin conjugate [1]
Saporin
Microtubule (MT)
Undisclosed
References
Ref 1 Novel antibody drug conjugate to inhibit mesothelioma tumor growth. Cancer Res (2019) 79 (13_Supplement): 210.