Antigen Information
General Information of This Antigen (ID: TAR0CZOZP)
| Antigen Name | Carbonic anhydrase 9 (CA9) |
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| Gene Name | CA9 |
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| Gene ID | ||||||
| Synonym | G250; MN; Carbonate dehydratase IX;Carbonic anhydrase IX;Membrane antigen MN;P54/58N;Renal cell carcinoma-associated antigen G250;pMW1 |
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| Sequence |
MAPLCPSPWLPLLIPAPAPGLTVQLLLSLLLLVPVHPQRLPRMQEDSPLGGGSSGEDDPL
GEEDLPSEEDSPREEDPPGEEDLPGEEDLPGEEDLPEVKPKSEEEGSLKLEDLPTVEAPG DPQEPQNNAHRDKEGDDQSHWRYGGDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPL ELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQLHLHWGAAGRPGSEHT VEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIA EEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQLHTLS DTLWGPGDSRLQLNFRATQPLNGRVIEASFPAGVDSSPRAAEPVQLNSCLAAGDILALVF GLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAETGA Click to Show/Hide
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| Family | Alkaline phosphatase family |
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| Function |
Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions).
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
3ee9
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
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BAY 79-4620
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Monomethyl auristatin E |
Microtubule (MT) |
Val-Cit dipeptide linker |
Undisclosed
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
WO2024043319A1 88
[1]
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Undisclosed |
Undisclosed |
Undisclosed |