Antigen Information
General Information of This Antigen (ID: TAR0CAWUI)
| Antigen Name | T-cell surface antigen CD2 (CD2) |
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| Gene Name | CD2 |
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| Gene ID | ||||||
| Synonym | SRBC; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD2 |
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| Sequence |
MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLDIPSFQMSDDIDDIKWE
KTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQDIYKVSIYDTKGKNVLEK IFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQDGKHLKLSQRVITHKWTTSL SAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICGGGSLLMVFVALLVFYITKRKKQ RSRRNDEELETRAHRVATEERGRKPHQIPASTPQNPATSQHPPPPPGHRSQAPSHRPPPP GHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQPKPPHGAAENSLSPSSN Click to Show/Hide
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| Function |
CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
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Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
Ab85 D265C/H435A
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
Ab85 D265C/H435A ADC A
[1]
|
Amaninamide (thioether) |
DNA-directed RNA polymerase II subunit RPB2 (POLR2B); DNA-directed RNA polymerase III subunit RPC7 (POLR3G) |
Mc-Val-Ala-PABC |
CD2 RPA2.10 D265C/H435A
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
CD2 RPA2.10 D265C/H435A ADC A
[1]
|
Amaninamide (thioether) |
DNA-directed RNA polymerase II subunit RPB2 (POLR2B); DNA-directed RNA polymerase III subunit RPC7 (POLR3G) |
Mc-Val-Ala-PABC |
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CD2 RPA2.10 D265C/H435A ADC C
[1]
|
Alpha-amanitin (thioether) |
DNA-directed RNA polymerase II subunit RPB2 (POLR2B); DNA-directed RNA polymerase III subunit RPC7 (POLR3G) |
Maleimido-caproyl |